免疫原
Synthesized peptide derived from part region of human protein
特异性
STAR3 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
StAR related lipid transfer domain containing 3(STARD3) Homo sapiens This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
功能
function:Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.,similarity:Contains 1 MENTAL domain.,similarity:Contains 1 START domain.,
基因名称(Gene Name)
STARD3 CAB1 MLN64
蛋白名称
StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)
Fields
>>Cholesterol metabolism
细胞定位
Late endosome membrane ; Multi-pass membrane protein . Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2. .
组织表达
Expressed in retina.