免疫原
Synthesized peptide derived from part region of human protein
特异性
ANFC Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015],
功能
function:Vasorelaxant activity. Has a cGMP-stimulating activity.,similarity:Belongs to the natriuretic peptide family.,
基因名称(Gene Name)
NPPC CNP2
蛋白名称
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
Fields
>>cGMP-PKG signaling pathway;>>Vascular smooth muscle contraction;>>Fluid shear stress and atherosclerosis
组织表达
[CNP-22]: In the kidney, predominantly expressed in the distal tubular cells (at protein level).