免疫原
Synthesized peptide derived from part region of human protein AA range: 181-231
特异性
MATR3 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
matrin 3(MATR3) Homo sapiens This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013],
功能
function:May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.,similarity:Contains 1 matrin-type zinc finger.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Part of complex consisting of SFPQ, NONO and MATR3.,
基因名称(Gene Name)
MATR3 KIAA0723
Fields
>>Amyotrophic lateral sclerosis
组织表达
Amygdala,Brain,Epithelium,Fetal kidney,Hypothalamus,Liver,Retina,Skin,