免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
P2RY2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
purinergic receptor P2Y2(P2RY2) Homo sapiens The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013],
功能
function:Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Spleen, testis, kidney, liver, lung, heart and brain.,
基因名称（Gene Name）
P2RY2 P2RU1
蛋白名称
P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (Purinergic receptor)
Fields
>>Neuroactive ligand-receptor interaction;>>Inflammatory mediator regulation of TRP channels
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Spleen, testis, kidney, liver, lung, heart and brain.
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