免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
CALRL Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,
功能
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,
基因名称(Gene Name)
CALCRL CGRPR
蛋白名称
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)
Fields
>>Neuroactive ligand-receptor interaction;>>Vascular smooth muscle contraction
细胞定位
Cell membrane ; Multi-pass membrane protein.
组织表达
Predominantly expressed in the lung and heart.