免疫原
Synthesized peptide derived from human protein . at AA range: 54-103
特异性
PF4V Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015],
功能
function:Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).,mass spectrometry:Platelet factor 4 variant PubMed:15459074,mass spectrometry:Platelet factor 4 variant(4-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(5-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(6-74) PubMed:15459074,PTM:The N-terminal processed forms of platelet factor 4 variant seems to be produced by proteolytic cleavage. The most abundant form is Platelet factor 4 variant(5-74).,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
基因名称（Gene Name）
PF4V1 CXCL4V1 SCYB4V1
蛋白名称
Platelet factor 4 variant (C-X-C motif chemokine 4 variant) (CXCL4L1) (PF4alt) (PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
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