免疫原
Synthesized peptide derived from human protein . at AA range: Internal
特异性
FXYD5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
FXYD domain containing ion transport regulator 5(FXYD5) Homo sapiens This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up
功能
function:Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.,PTM:Glycosylated.,similarity:Belongs to the FXYD family.,
基因名称（Gene Name）
FXYD5 DYSAD IWU1 HSPC113 UNQ2561/PRO6241
蛋白名称
FXYD domain-containing ion transport regulator 5 (Dysadherin)
细胞定位
Membrane ; Single-pass type I membrane protein .
组织表达
Bone marrow,Leukocyte,Pancreas,Umbilical cord blood,
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