免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
SMAGP Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
功能
function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
蛋白名称
Small cell adhesion glycoprotein (Small transmembrane and glycosylated protein)
细胞定位
Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle membrane ; Single-pass type III membrane protein . Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). .
组织表达
Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).