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THOP1 Polyclonal Antibody

说明书

BYab-06921

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
75kD
免疫原
Synthesized peptide derived from part region of human protein
特异性
THOP1 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015],
功能
catalytic activity:Preferential cleavage of bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues.,cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 1 zinc ion.,function:Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.,similarity:Belongs to the peptidase M3 family.,subunit:Monomer.,
基因名称(Gene Name)
THOP1
蛋白名称
Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78)
简称
THOP1
其他名称
Fields
>>Renin-angiotensin system;>>African trypanosomiasis
人基因ID
7064
人蛋白质序列数据库
P52888
小鼠基因ID
小鼠蛋白质序列数据库
Q8C1A5
大鼠基因ID
大鼠蛋白质序列数据库
P24155
细胞定位
Cytoplasm.
组织表达
Brain,Lung,Placenta,Uterus,
储存(Storage)
-20°C/1 year

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THOP1 Polyclonal Antibody

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