免疫原
Synthesized peptide derived from part region of human protein
特异性
NFIP2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:May be involved in endocytosis. Regulates ENaC surface expression (By similarity). May be involved in NF-kappa-B and MAPK signaling pathways.,induction:By T-cell activation.,PTM:Ubiquitinated by NEDD4 or NEDD4L; which does not affect turnover.,subunit:Interacts with NEDD4L (By similarity). Interacts with NEDD4.,tissue specificity:Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.,
功能
function:May be involved in endocytosis. Regulates ENaC surface expression (By similarity). May be involved in NF-kappa-B and MAPK signaling pathways.,induction:By T-cell activation.,PTM:Ubiquitinated by NEDD4 or NEDD4L; which does not affect turnover.,subunit:Interacts with NEDD4L (By similarity). Interacts with NEDD4.,tissue specificity:Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.,
基因名称(Gene Name)
NDFIP2 KIAA1165 N4WBP5A
蛋白名称
NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413)
细胞定位
Endosome membrane ; Multi-pass membrane protein . Golgi apparatus membrane . Endosome, multivesicular body membrane .
组织表达
Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.