免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
GBP2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013],
功能
function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.,induction:By interferon gamma during macrophage activation.,similarity:Belongs to the GBP family.,
蛋白名称
Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2)
Fields
>>NOD-like receptor signaling pathway
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Membrane; Lipid-anchor . Cytoplasmic vesicle . GBP2-GBP5 dimers localize to the Golgi apparatus. .
组织表达
Foreskin,Lung,Skin,Spinal cord,Thymus,
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