免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
BIN2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
induction:Up-regulated during monocytic differentiation.,similarity:Contains 1 BAR domain.,subunit:Interacts with BIN1.,tissue specificity:Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.,
功能
induction:Up-regulated during monocytic differentiation.,similarity:Contains 1 BAR domain.,subunit:Interacts with BIN1.,tissue specificity:Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.,
基因名称（Gene Name）
BIN2 BRAP1
蛋白名称
Bridging integrator 2 (Breast cancer-associated protein 1)
细胞定位
Cytoplasm . Cell projection, podosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cell projection, phagocytic cup . Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure. .
组织表达
Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
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