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WNT8B Polyclonal Antibody

说明书

BYab-06542

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
38kD
免疫原
Synthesized peptide derived from part region of human protein
特异性
WNT8B Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008],
功能
function:Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.,similarity:Belongs to the Wnt family.,tissue specificity:Expression is restricted to the brain, and more specifically to the forebrain.,
基因名称(Gene Name)
WNT8B
蛋白名称
Protein Wnt-8b
简称
WNT8B
其他名称
Fields
>>mTOR signaling pathway;>>Wnt signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
人基因ID
7479
人蛋白质序列数据库
Q93098
小鼠基因ID
小鼠蛋白质序列数据库
Q9WUD6
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted, extracellular space, extracellular matrix.
组织表达
Expression is restricted to the brain, and more specifically to the forebrain.
储存(Storage)
-20°C/1 year

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WNT8B Polyclonal Antibody

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