免疫原
Synthesized peptide derived from part region of human protein
特异性
S39A5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
功能
function:May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status.,PTM:Glycosylated.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.,
基因名称(Gene Name)
SLC39A5 ZIP5
蛋白名称
Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)
Fields
>>Alzheimer disease;>>Parkinson disease
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
组织表达
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.