免疫原
Synthesized peptide derived from part region of human protein
特异性
ZN238 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of chromatin to target genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
功能
function:Sequence-specific DNA-binding protein with transcriptional repression activity. Binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. May play a role in the organization of chromosomes in the nucleus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associates with condensed chromatin.,subunit:Interacts with DNMT3A.,tissue specificity:Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.,
基因名称（Gene Name）
ZNF238 RP58 TAZ1 ZBTB18
蛋白名称
Zinc finger protein 238 (58 kDa repressor protein) (Transcriptional repressor RP58) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger and BTB domain-containing protein 18) (Zinc finger
细胞定位
Nucleus. Associates with condensed chromatin.
组织表达
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
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