免疫原
Synthesized peptide derived from part region of human protein
特异性
TRAK1 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,
功能
PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,
基因名称(Gene Name)
TRAK1 KIAA1042 OIP106
蛋白名称
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)
细胞定位
Cytoplasm . Nucleus . Mitochondrion . Early endosome . Endosome . Mitochondrion membrane . Cytoplasm, cell cortex . Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HGS/HRS (PubMed:18675823). Colocalizes with MGARP at the mitochondria (PubMed:19528298). .
组织表达
High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.