SF3A3 Polyclonal Antibody

说明书

BYab-06230

20UL ￥460 50UL ￥945 100UL ￥1350
货期： 3天左右

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宿主

反应性

应用

WB;ELISA

分子量（DA）

55kD

免疫原

Synthesized peptide derived from part region of human protein

特异性

SF3A3 Polyclonal Antibody detects endogenous levels of protein.

来源

Polyclonal, Rabbit,IgG

组成（Formulation）

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

稀释比例

WB 1:500-2000 ELISA 1:5000-20000

纯化工艺（Immunogen）

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度

1 mg/ml

背景（Background）

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

功能

function:Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.,similarity:Belongs to the SF3A3 family.,similarity:Contains 1 matrin-type zinc finger.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B

基因名称（Gene Name）

SF3A3 SAP61

蛋白名称

Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61)

SF3A3 Polyclonal Antibody

BYab-06230

产品简介>

宿主

反应性

应用

分子量（DA）

免疫原

特异性

来源

组成（Formulation）

稀释比例

纯化工艺（Immunogen）

浓度

背景（Background）

功能

基因名称（Gene Name）

蛋白名称

简称

其他名称

Fields

人基因ID

人蛋白质序列数据库

小鼠基因ID

小鼠蛋白质序列数据库

大鼠基因ID

大鼠蛋白质序列数据库

细胞定位

组织表达

储存（Storage）

实验方案>

引用文献(0)>

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SF3A3 Polyclonal Antibody

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