免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
PPME1 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
功能
function:Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).,sequence caution:Wrong choice of CDS.,similarity:Belongs to the AB hydrolase superfamily.,subunit:Binds PPP2CB.,
基因名称(Gene Name)
PPME1 PME1 PP2593 PRO0750
蛋白名称
Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)
细胞定位
cell-cell adherens junction,
组织表达
Amygdala,Cervix carcinoma,Fetal liver,Lung,Platelet,Skin,