免疫原
Synthesized peptide derived from human protein . at AA range: 1880-1960
特异性
NBAS Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
IHC-p 1:50-300. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012],
功能
sequence caution:Translated as stop.,sequence caution:Translation N-terminally extended.,similarity:Contains 2 WD repeats.,tissue specificity:Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small inntestine and thymus. Up-regulated together with N-myc in some neuroblastoma cell lines.,
蛋白名称
Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein)
细胞定位
Cytoplasm . Endoplasmic reticulum . Endoplasmic reticulum membrane; Peripheral membrane protein .
组织表达
Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines.