免疫原
Synthesized peptide derived from human protein . at AA range: 370-450
特异性
MYO1A Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011],
功能
disease:Defects in MYO1A are the cause of non-syndromic sensorineural deafness autosomal dominant type 48 (DFNA48) [MIM:607841]. DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.,function:Involved in directing the movement of organelles along actin filaments .,similarity:Contains 1 myosin head-like domain.,similarity:Contains 3 IQ domains.,
基因名称（Gene Name）
MYO1A MYHL
蛋白名称
Unconventional myosin-Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC)
Fields
>>Pathogenic Escherichia coli infection
细胞定位
cytoplasm,microvillus,brush border,basal plasma membrane,basolateral plasma membrane,apical plasma membrane,lateral plasma membrane,myosin complex,cortical actin cytoskeleton,filamentous actin,plasma membrane raft,
组织表达
Intestine,Jejunum,Placenta,
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