免疫原
Synthesized peptide derived from part region of human protein
特异性
ICAM5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008],
功能
function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 9 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.,
基因名称（Gene Name）
ICAM5 TLCN TLN
蛋白名称
Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
细胞定位
Membrane; Single-pass type I membrane protein.
组织表达
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
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