免疫原
Synthesized peptide derived from part region of human protein
特异性
GNA12 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
蛋白名称
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Fields
>>MAPK signaling pathway;>>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Phospholipase D signaling pathway;>>Vascular smooth muscle contraction;>>Long-term depression;>>Regulation of actin cytoskeleton;>>Parathyroid hormone synthesis, secretion and action;>>Pathogenic Escherichia coli infection;>>Human cytomegalovirus infection;>>Pathways in cancer
细胞定位
Cell membrane ; Lipid-anchor . Lateral cell membrane ; Lipid-anchor . Cytoplasm . CDH1 enhances cell membrane localization. .
组织表达
Brain,Pancreas,Placenta,Uterus,