免疫原
Synthesized peptide derived from part region of human protein
特异性
EDEM3 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008],
功能
domain:Contains a protease-associated domain (PA) of unknown function.,function:Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity.,PTM:N-glycosylated.,similarity:Belongs to the glycosyl hydrolase 47 family.,similarity:Contains 1 PA (protease associated) domain.,
基因名称（Gene Name）
EDEM3 C1orf22
蛋白名称
ER degradation-enhancing alpha-mannosidase-like 3
Fields
>>Protein processing in endoplasmic reticulum
细胞定位
Endoplasmic reticulum lumen .
组织表达
Brain,Liver,Lung,Placenta,Testis,Whole embr
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
