免疫原
Synthesized peptide derived from part region of human protein
特异性
CCDC8 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011],
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,
蛋白名称
Coiled-coil domain-containing protein 8
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
组织表达
Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver.
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