免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
K22O Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jun 2009],
功能
developmental stage:Synthesized during maturation of epidermal keratinocytes.,function:Probably contributes to terminal cornification.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,sequence caution:Translated as Glu.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,
基因名称(Gene Name)
KRT76 KRT2B KRT2P
蛋白名称
Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (CK-2P) (K2P) (Keratin-76) (K76) (Type-II keratin Kb9)
细胞定位
nucleus,intermediate filament,keratin filament,extracellular exosome,