免疫原
Synthesized peptide derived from human protein . at AA range: 470-550
特异性
HSP72 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
功能
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
蛋白名称
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2)
Fields
>>Spliceosome;>>MAPK signaling pathway;>>Protein processing in endoplasmic reticulum;>>Endocytosis;>>Longevity regulating pathway - multiple species;>>Antigen processing and presentation;>>Estrogen signaling pathway;>>Prion disease;>>Legionellosis;>>Toxoplasmosis;>>Measles;>>Lipid and atherosclerosis
细胞定位
Cytoplasm, cytoskeleton, spindle . Colocalizes with SHCBP1L at spindle during the meiosis process. .
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