免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
ABC3C Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008],
功能
cofactor:Zinc.,function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.,
基因名称(Gene Name)
APOBEC3C APOBEC1L PBI
蛋白名称
Probable DNA dC->dU-editing enzyme APOBEC-3C (EC 3.5.4.-) (APOBEC1-like) (Phorbolin I)
Fields
>>Viral life cycle - HIV-1;>>Human immunodeficiency virus 1 infection
细胞定位
Nucleus . Cytoplasm .
组织表达
Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.