免疫原
Synthesized peptide derived from human protein . at AA range: 440-520
特异性
BORA Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008],
功能
function:Required for the activation of Aurora-A (AURKA/STK6) at the onset of mitosis.,PTM:Phosphorylated by AURKA/STK6.,similarity:Belongs to the BORA family.,subunit:Interacts with AURKA/STK6.,
基因名称(Gene Name)
BORA C13orf34
蛋白名称
Protein aurora borealis (HsBora)
细胞定位
cytosol,meiotic spindle,
组织表达
Bone marrow,Leiomyosarcoma,Rhabdomyosarcoma,Small intestine,Testis carcinom