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NFAT5 Mouse mAb(1D6)

说明书

BYab-04788

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;WB
分子量(DA)
200kD
免疫原
Synthesized peptide derived from human NFAT5
特异性
This antibody detects endogenous levels of NFAT5 at Human, Mouse,Rat
来源
Monoclonal, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.26% sodium azide.
稀释比例
IHC-p1:50-200 ,WB 1:1000-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.,similarity:Contains 1 RHD (Rel-like) domain.,subunit:Does not bind with Fos and Jun transcription factors. But might be capable of forming stable dimers with DNA elements.,tissue specificity:Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.,
基因名称(Gene Name)
NFAT5 KIAA0827 TONEBP
蛋白名称
NFAT5
简称
NFAT5
其他名称
Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) (Tonicity-responsive enhancer-binding protein) (TonE-binding protein) (TonEBP)
Fields
人基因ID
10725
人蛋白质序列数据库
O94916
小鼠基因ID
小鼠蛋白质序列数据库
Q9WV30
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus . Cytoplasm . Nuclear distribution increases under hypertonic conditions. .
组织表达
Widely expressed, with highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes.
储存(Storage)
-20°C/1 year

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NFAT5 Mouse mAb(1D6)

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