免疫原
Synthesized peptide derived from human Histone H1 (Acetyl Lys66/63/64)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Histone H1 (Acetyl Lys66/63/64)
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],
功能
function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.,similarity:Belongs to the histone H1/H5 family.,
基因名称（Gene Name）
HIST1H1A H1F1
蛋白名称
Histone H1 (Acetyl Lys66/63/64)
其他名称
Histone H1.1 (Histone H1a)
人蛋白质序列数据库
Q02539/P16403/P16402/P10412
细胞定位
Nucleus . Chromosome . Mainly localizes in euchromatin.
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