免疫原
Synthesized peptide derived from human ACSS2 (Acetyl Lys418)
特异性
This antibody detects endogenous levels of Human,Mouse ACSS2 (Acetyl Lys418)
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
功能
catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
基因名称（Gene Name）
ACSS2 ACAS2
蛋白名称
ACSS2 (Acetyl Lys418)
其他名称
Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1;Acetate--CoA ligase;Acetyl-CoA synthetase;ACS;AceCS;Acyl-CoA synthetase short-chain family member 2;Acyl-activating enzyme)
Fields
>>Glycolysis / Gluconeogenesis;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Propanoate metabolism;>>Metabolic pathways;>>Carbon metabolism
细胞定位
Cytoplasm, cytosol .
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