免疫原
Synthesized peptide derived from human NOTCH3 (Cleaved-Val1662)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat NOTCH3 (Cleaved-Val1662, protein was cleaved amino acid sequence between 1661-1662 )
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
蛋白名称
NOTCH3 (Cleaved-Val1662)
其他名称
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Fields
>>Endocrine resistance;>>Notch signaling pathway;>>Apelin signaling pathway;>>Th1 and Th2 cell differentiation;>>Thyroid hormone signaling pathway;>>Human papillomavirus infection;>>Pathways in cancer;>>MicroRNAs in cancer;>>Breast cancer
细胞定位
Cell membrane ; Single-pass type I membrane protein.; [Notch 3 intracellular domain]: Nucleus. Following proteolytical processing NICD is translocated to the nucleus.
组织表达
Ubiquitously expressed in fetal and adult tissues.