免疫原
The antiserum was produced against synthesized peptide derived from human SEPT14. AA range:341-390
特异性
Septin 14 Polyclonal Antibody detects endogenous levels of Septin 14 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008],
功能
function:Involved in cytokinesis .,similarity:Belongs to the septin family.,
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Perikaryon . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalizes with actin stress fibers (PubMed:17922164). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). .
组织表达
Testis-specific (at protein level).