免疫原
The antiserum was produced against synthesized peptide derived from human CSGALNACT2. AA range:61-110
特异性
CsGalNAcT-2 Polyclonal Antibody detects endogenous levels of CsGalNAcT-2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome X. [provided by RefSeq, Feb 2016],
功能
catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-(1->3)-beta-D-galactosylproteoglycan.,function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains.,online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2,online information:GlycoGene database,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,tissue specificity:Ubiquitous.,
基因名称(Gene Name)
CSGALNACT2
蛋白名称
Chondroitin sulfate N-acetylgalactosaminyltransferase 2
其他名称
CSGALNACT2; CHGN2; GALNACT2; Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
Fields
>>Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate;>>Metabolic pathways
细胞定位
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein .