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CHST9 Polyclonal Antibody

说明书

BYab-03774

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;IF;ELISA
分子量(DA)
免疫原
The antiserum was produced against synthesized peptide derived from human CHST9. AA range:361-410
特异性
CHST9 Polyclonal Antibody detects endogenous levels of CHST9 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011],
功能
caution:It is uncertain whether Met-1 or Met-8 is the initiator.,function:Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.,
基因名称(Gene Name)
CHST9
蛋白名称
Carbohydrate sulfotransferase 9
简称
CHST9
其他名称
CHST9; Carbohydrate sulfotransferase 9; GalNAc-4-O-sulfotransferase 2; GalNAc-4-ST2; GalNAc4ST-2; N-acetylgalactosamine-4-O-sulfotransferase 2
Fields
>>Various types of N-glycan biosynthesis;>>Metabolic pathways
人基因ID
83539
人蛋白质序列数据库
Q7L1S5
小鼠基因ID
71367
小鼠蛋白质序列数据库
Q76EC5
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
[Isoform 1]: Golgi apparatus membrane ; Single-pass type II membrane protein .; [Isoform 2]: Secreted .
组织表达
Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.
储存(Storage)
-20°C/1 year

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CHST9 Polyclonal Antibody

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