免疫原
The antiserum was produced against synthesized peptide derived from human CHST13. AA range:211-260
特异性
CHST13 Polyclonal Antibody detects endogenous levels of CHST13 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011],
功能
catalytic activity:3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.,function:Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney.,
蛋白名称
Carbohydrate sulfotransferase 13
其他名称
CHST13; Carbohydrate sulfotransferase 13; Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; C4ST-3; C4ST3
Fields
>>Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
组织表达
Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney.
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