免疫原
The antiserum was produced against synthesized peptide derived from human BAI2. AA range:91-140
特异性
BAI-2 Polyclonal Antibody detects endogenous levels of BAI-2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
功能
function:Might be involved in angiogenesis inhibition.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,subunit:Interacts with GABPB2.,tissue specificity:Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.,
蛋白名称
Brain-specific angiogenesis inhibitor 2
其他名称
BAI2; Brain-specific angiogenesis inhibitor 2
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.