免疫原
The antiserum was produced against synthesized peptide derived from human Annexin III. AA range:15-64
特异性
Annexin III Polyclonal Antibody detects endogenous levels of Annexin III protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008],
功能
domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,
其他名称
ANXA3; ANX3; Annexin A3; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III
细胞定位
cytoplasm,plasma membrane,membrane,axon,dendrite,phagocytic vesicle membrane,specific granule,neuronal cell body,extracellular exosome,
组织表达
Aorta endothelial cell,Cervix,Colon carcinoma,Platelet,