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Annexin VI mouse mAb

说明书

BYab-03465

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB
分子量(DA)
76kD
免疫原
Purified recombinant human Annexin VI protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Annexin VI and does not cross-react with related proteins.
来源
Monoclonal, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
wb 1:1000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010],
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.,induction:By EBV.,miscellaneous:Seems to bind one calcium ion with high affinity.,PTM:Phosphorylated in response to growth factor stimulation.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,similarity:Contains 8 annexin repeats.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
基因名称(Gene Name)
anxa6
蛋白名称
简称
Annexin VI
其他名称
67 kDa calelectrin;Annexin A6;Annexin VI;Annexin VI p68;Annexin-6;AnnexinA6;AnnexinVI; ANX 6;ANX A6;ANX6;ANXA6;ANXA6_HUMAN;Calcium binding protein p68;Calelectrin;Calphobindin II;Calphobindin-II;CalphobindinII;CBP 68;Chromobindin 20;CPBII;Lipocortin VI; LipocortinVI;Protein III;ProteinIII.
Fields
人基因ID
309
人蛋白质序列数据库
P08133
小鼠基因ID
小鼠蛋白质序列数据库
P14824
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
组织表达
Adipocyte,Amygdala,Lung,Uterus,
储存(Storage)
-20°C/1 year

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Annexin VI mouse mAb

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