欢迎访问南京博研生物官网 服务热线:025-52298998 |
您当前的位置: 首页 > 产品中心 > 一抗 > 单克隆抗体

Hsp70(C-term) mouse mAb

说明书

BYab-03451

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

产品简介 实验方案 引用文献 相关产品

产品简介>

宿主
反应性
应用
WB;IP
分子量(DA)
70kD
免疫原
Purified recombinant human Hsp70(C-terminus) protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Hsp70(C-terminus) and does not cross-react with related proteins.
来源
Monoclonal, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
wb 1:1000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008],
功能
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.,induction:By heat shock.,similarity:Belongs to the heat shock protein 70 family.,subunit:HSPA1B is found in a sperm-specific complex with CATSPER1 and CATSPERB (By similarity). Interacts with TSC2. Interacts with IRAK1BP1.,tissue specificity:HSPA1B is testis-specific
基因名称(Gene Name)
hspa1a
蛋白名称
简称
HSP70
其他名称
DAQB 147D11.1 001;FLJ54303;FLJ54370;FLJ54392;FLJ54408;FLJ75127;Heat shock 70 kDa protein 1;Heat shock 70 kDa protein 1/2;Heat shock 70 kDa protein 1A/1B;heat shock 70kDa protein 1A;Heat shock 70kDa protein 1B;Heat shock induced protein;heat shock protein 70;HSP70 1;HSP70 2;HSP70-1/HSP70-2;HSP70-1A;HSP70.1;HSP70.1/HSP70.2;HSP70I;HSP71_HUMAN;HSP72; HSPA1;HSPA1A;HSPA1B;XXbac BCX40G17.3 001.
Fields
>>Spliceosome;>>MAPK signaling pathway;>>Protein processing in endoplasmic reticulum;>>Endocytosis;>>Longevity regulating pathway - multiple species;>>Antigen processing and presentation;>>Estrogen signaling pathway;>>Prion disease;>>Legionellosis;>>Toxoplasmosis;>>Measles;>>Lipid and atherosclerosis
人基因ID
3303
人蛋白质序列数据库
P0DMV8/P0DMV9
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
组织表达
Brain,Cajal-Retzius cell,Embryonic kidney,Epithelium,Fetal
储存(Storage)
-20°C/1 year

实验方案>

实验步骤

引用文献(0)>

相关产品>

成功添加到购物车

查看购物车 继续购物

Hsp70(C-term) mouse mAb

筛选器: All

亮暗模式切换
X

在线
客服

在线客服
09:00 - 18:00

服务热线

服务
热线

客服服务热线

025-52298998
客服服务热线

扫码

扫码
咨询

微信二维码 微信扫一扫立即咨询
返回顶部 顶部