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Wnt-10b Monoclonal Antibody

说明书

BYab-03427

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;IHC;IF;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human Wnt-10b expressed in E. Coli.
特异性
Wnt-10b Monoclonal Antibody detects endogenous levels of Wnt-10b protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008],
功能
developmental stage:Infant brain has higher levels of WNT10B than adult brain.,function:Ligand for members of the frizzled family of seven transmembrane receptors.,function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,tissue specificity:Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain.,
基因名称(Gene Name)
WNT10B
蛋白名称
Protein Wnt-10b
简称
Wnt-10b
其他名称
WNT10B; WNT12; Protein Wnt-10b; Protein Wnt-12
Fields
>>mTOR signaling pathway;>>Wnt signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
人基因ID
7480
人蛋白质序列数据库
O00744
小鼠基因ID
小鼠蛋白质序列数据库
P48614
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
组织表达
Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain.
储存(Storage)
-20°C/1 year

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Wnt-10b Monoclonal Antibody

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