免疫原
The antiserum was produced against synthesized peptide derived from human MAP9. AA range:121-170
特异性
MAP-9 Polyclonal Antibody detects endogenous levels of MAP-9 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008],
功能
developmental stage:Constitutively expressed during the cell cycle.,function:Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.,subunit:Binds to purified microtubules via its C-terminus.,
蛋白名称
Microtubule-associated protein 9
其他名称
MAP9; ASAP; Microtubule-associated protein 9; Aster-associated protein
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
组织表达
Amygdala,Bone marrow,Brain,