免疫原
The antiserum was produced against synthesized peptide derived from human KIF13B. AA range:111-160
特异性
KIF13B Polyclonal Antibody detects endogenous levels of KIF13B protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 CAP-Gly domain.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Binds to DLG1 and DLG4.,tissue specificity:Ubiquitous.,
功能
function:May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 CAP-Gly domain.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Binds to DLG1 and DLG4.,tissue specificity:Ubiquitous.,
蛋白名称
Kinesin-like protein KIF13B
其他名称
KIF13B; GAKIN; KIAA0639; Kinesin-like protein KIF13B; Kinesin-like protein GAKIN
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon . accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.