免疫原
The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500
特异性
RN-tre Polyclonal Antibody detects endogenous levels of RN-tre protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,
功能
function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,
蛋白名称
USP6 N-terminal-like protein
其他名称
USP6NL; KIAA0019; USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre
细胞定位
Golgi apparatus. Cytoplasmic vesicle.