免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2W1. AA range:311-360
特异性
CYP2W1 Polyclonal Antibody detects endogenous levels of CYP2W1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008],
功能
cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,
其他名称
CYP2W1; Cytochrome P450 2W1; CYPIIW1
Fields
>>Retinol metabolism;>>Metabolic pathways
细胞定位
Endoplasmic reticulum lumen . Cell membrane . Microsome membrane . About 8% are expressed on the cell surface. .
组织表达
Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.