免疫原
The antiserum was produced against synthesized peptide derived from human CBR3. AA range:151-200
特异性
Carbonyl Reductase 3 Polyclonal Antibody detects endogenous levels of Carbonyl Reductase 3 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008],
功能
catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
蛋白名称
Carbonyl reductase [NADPH] 3
其他名称
CBR3; Carbonyl reductase [NADPH] 3; NADPH-dependent carbonyl reductase 3
Fields
>>Arachidonic acid metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Metabolic pathways
组织表达
Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.