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CBR1 mouse mAb

说明书

BYab-02368

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ICC
分子量(DA)
30kD
免疫原
Purified recombinant human CBR1 protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of CBR1 and does not cross-react with related proteins.
来源
Monoclonal, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
wb 1:1000 icc 1:100
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],
功能
catalytic activity:(13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NADP(+) = (13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADPH.,catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP(+) = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.,catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Catalyzes the reduction of a wide variety of carbonyl compounds including the antitumor anthracycline antibiotics. Can convert prostaglandin E2 to prostaglandin F2-alpha.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Monomer.,
基因名称(Gene Name)
cbr1
蛋白名称
简称
CBR1
其他名称
15 hydroxyprostaglandin dehydrogenase [NADP ];15-hydroxyprostaglandin dehydrogenase [NADP ];Carbonyl reductase [NADPH] 1;CBR 1;CBR1;CBR1_HUMAN;CRN;NADPH dependent carbonyl reductase 1;NADPH-dependent carbonyl reductase 1;Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase;Prostaglandin E(2) 9 reductase;Prostaglandin-E(2) 9-reductase;SDR21C1.
Fields
>>Arachidonic acid metabolism;>>Folate biosynthesis;>>Metabolism of xenobiotics by cytochrome P450;>>Metabolic pathways;>>Chemical carcinogenesis - DNA adducts;>>Chemical carcinogenesis - reactive oxygen species
人基因ID
873
人蛋白质序列数据库
P16152
小鼠基因ID
小鼠蛋白质序列数据库
P48758
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm .
组织表达
Expressed in kidney (at protein level).
储存(Storage)
-20°C/1 year

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CBR1 mouse mAb

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