免疫原
Synthesized peptide derived from ZNHIT1 . at AA range: 40-120
特异性
ZNHIT1 Polyclonal Antibody detects endogenous levels of ZNHIT1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
功能
function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
蛋白名称
Zinc finger HIT domain-containing protein 1
其他名称
ZNHIT1; CGBP1; ZNFN4A1; Zinc finger HIT domain-containing protein 1; Cyclin-G1-binding protein 1; Zinc finger protein subfamily 4A member 1; p18 Hamlet
组织表达
Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.