hnRNP M Polyclonal Antibody

宿主

反应性

应用

WB;IHC;IF;ELISA

分子量（DA）

78kD

免疫原

The antiserum was produced against synthesized peptide derived from human hnRNP M. AA range:11-60

特异性

hnRNP M Polyclonal Antibody detects endogenous levels of hnRNP M protein.

来源

Polyclonal, Rabbit,IgG

组成（Formulation）

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

稀释比例

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

纯化工艺（Immunogen）

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度

1 mg/ml

背景（Background）

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provide

功能

alternative products:Experimental confirmation may be lacking for some isoforms,function:Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.,PTM:Sumoylated.,similarity:Contains 3 RRM (RNA recognition motif) domains.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRNPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B

基因名称（Gene Name）

HNRNPM

蛋白名称

Heterogeneous nuclear ribonucleoprotein M

简称

hnRNP M

其他名称

HNRNPM; HNRPM; NAGR1; Heterogeneous nuclear ribonucleoprotein M; hnRNP M

Fields

>>Spliceosome

人基因ID

4670

人蛋白质序列数据库

P52272

小鼠基因ID

76936

小鼠蛋白质序列数据库

Q9D0E1

大鼠基因ID

116655

大鼠蛋白质序列数据库

Q62826

细胞定位

Nucleus, nucleolus .

组织表达

Brain,Cervix carcinoma,Duodenum,Epithelium,Lymph,Placenta,T

储存（Storage）

-20°C/1 year

BYab-01811

产品简介>

宿主

反应性

应用

分子量（DA）

免疫原

特异性

来源

组成（Formulation）

稀释比例

纯化工艺（Immunogen）

浓度

背景（Background）

功能

基因名称（Gene Name）

蛋白名称

简称

其他名称

Fields

人基因ID

人蛋白质序列数据库

小鼠基因ID

小鼠蛋白质序列数据库

大鼠基因ID

大鼠蛋白质序列数据库

细胞定位

组织表达

储存（Storage）

实验方案>

引用文献(0)>

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hnRNP M Polyclonal Antibody

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