免疫原
The antiserum was produced against synthesized peptide derived from human EEF1G. AA range:101-150
特异性
EF-1 γ Polyclonal Antibody detects endogenous levels of EF-1 γ protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
eukaryotic translation elongation factor 1 gamma(EEF1G) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008],
功能
function:Probably plays a role in anchoring the complex to other cellular components.,similarity:Contains 1 EF-1-gamma C-terminal domain.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:EF-1 is composed of four subunits: alpha, beta, delta, and gamma.,tissue specificity:Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.,
蛋白名称
Elongation factor 1-gamma
其他名称
EEF1G; EF1G; Elongation factor 1-gamma; EF-1-gamma; eEF-1B gamma
细胞定位
nucleus,cytoplasm,endoplasmic reticulum,cytosol,cell-cell adherens junction,membrane,extracellular exosome,
组织表达
Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.